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“The Brain Care Score is a simple tool designed to help anyone in the world answer the question, ‘What can I do to take better care of my brain?’” said study author Dr. Jonathan Rosand, cofounder of the McCance Center for Brain Health at Massachusetts General Hospital and lead developer of the BCS,in a news release.

“This paper provides compelling evidence that raising your BCS is not only likely to make your brain healthier and more resistant to diseases like dementia and stroke, but that it also offers the hope of protection from depression,” added Rosand, a professor of neurology at Harvard Medical School in Boston.

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Up to one-third or more of people older than 60 experience late-life depression, the risk of which can be influenced by lifestyle habits, the authors said.

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For participants of the new study, every five-point positive difference in their BCS was associated with a 33% lower risk of late-life depression, as well as a 27% lower composite risk of late-life depression, dementia and stroke over a follow-up period of 13 years on average.

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“People think of the skull as like a separating factor for the brain, (as if) the brain is like an individual thing,” said Dr. Richard Isaacson, a preventive neurologist at the Institute for Neurodegenerative Diseases in Florida who wasn’t involved in the study. “But it’s clear, based on this study and others, that if we can stay physically active, eat a healthy diet, minimize smoking and alcohol, keep a healthy weight and stay socially engaged, there’s going to be downstream benefits — not just on vascular health and dementia, but also for mental health and emotional health.”

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But the association among younger adults falls in line with the life trajectory of other diseases associated with age, Isaacson said.

“In our Alzheimer’s prevention clinic, we’ve been seeing people age 25 and up,” Isaacson said. “That finding is not surprising to me, because there are early life, midlife and late-life risk factors for dementia. (For) Alzheimer’s disease, for example, pathology starts in the brain decades before symptoms of memory loss. If a person is 65 years old and diagnosed with dementia, that means the disease first started in their brains between the ages of 35 to 45.”

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“There is still much to be learned about what pathways contribute to late-life depression, dementia and stroke,” said Dr. Sanjula Singh, first author of the study and instructor at the McCance Center for Brain Health, in a news release. “Our results emphasize the importance of a holistic view of the brain to further understand underlying connections between different brain diseases.”

If you’re an older adultexperiencing depression, know that being open and seeking care is critical, Isaacson said.

“Older generations may have been primed to just fight through it, (thinking) it’s mind over matter,” Isaacson said. But that’s not always the case, he added, so try to accept that you’re not feeling OK and talk with your doctor about treatment options such as therapy or antidepressants.

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