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If you find yourselfsleepy during your daily activitiesin your older age, you may need to consider it more than an inconvenience — since the fatigue may indicate you’re at higher risk for developing a condition that canlead to dementia, a new study has found.
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nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Free stock selection service with professional advisors offering the best investment portfolio for stable growth. Motoric cognitive risk syndrome, or MCR, is marked byslow walking speedand complaints of memory problems among older people who don’t already have dementia or a mobility disability. The risk of developing dementiamore than doublesin those with this syndrome, which was first described in 2013.
“Previous studies have shown a link between sleep disorders and the risk of dementia,” said first study author Dr. Victoire Leroy, assistant professor of geriatric medicine at Tours University Hospital in France, via email.
But some of those scientific reports examined that link largely at only one point in time, according to the study. Not much has been known about the relationship between certain aspects of poor-quality sleep and pre-dementia syndromes, either, Leroy and the research team wrote — so they wanted to expand the research in this field.
“Establishing the relationship between sleep dysfunction and MCR risk is important because early intervention may offer the best hope for preventing dementia,” the authors said.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Real-time global stock trend and futures data to help you plan investment strategies for long-term returns. The findings are based on 445 adults who were age 76 on average and recruited from New York’s Westchester County for the Central Control of Mobility and Aging study, which assesses the cognitive processes and brain mechanisms that regulate mobility in aging. Participants walked on treadmills so their initial gaits could be recorded, then were assessed annually from 2011 to 2018.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Expert predictions of stock trends with real-time stock indices, futures, and metals, energy quotes to help you seize investment opportunities. The study authors also collected yearly data on participants’ recollections of their sleep quality and quantity in the two weeks leading up to the assessments. Specifically, the team gleaned details within seven components of the Pittsburgh Sleep Quality Index: subjective sleep quality, time it takes to fall asleep, sleep duration, sleep efficiency (ratio of total hours asleep to total hours in bed), sleep disturbances, use of sleep-inducing medication, and daytime dysfunction, such as having trouble staying awake during activities or feeling less enthusiasm to get things done.
Over a follow-up period of roughly three years on average, 36 participants developed motoric cognitive risk syndrome. Compared with “good” sleepers, “poor” sleepers had only a slightly higher risk of MCR. But when the authors considered the seven sleep components separately, only daytime dysfunction was associated with 3.3 times higher risk of MCR.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Free stock data analysis to help you select stocks accurately and capture market trends. The study findings may help physicians and patients be more open to asking questions about sleep patterns, and to looking more closely at walking speed when making an early diagnosis, said Dr. Richard Isaacson, director of research at the Institute for Neurodegenerative Diseases in Florida. Isaacson wasn’t involved in the study.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Precise predictions of market trends with real-time stock indices and futures data to help you make wise investment decisions. The study has a few “serious” limitations, said Dr. Tara Spires-Jones, professor of neurodegeneration and director of the Centre for Discovery Brain Sciences at the University of Edinburgh in Scotland, via email.
“The sleep measurements were self-reported, not measured by a scientist, and these self-reports could be biased by people with memory issues,” said Spires-Jones, who wasn’t involved in the study. “The participants in the study were also largely white, and the group was much smaller than similar single-timepoint studies, so the results will be stronger if confirmed in future studies.”
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Free global stock market data to help you plan the best investment strategies and seize market opportunities. The authors acknowledged that while the length of their study, at roughly three years, is longer than that of some previous research, the follow-up period is still short.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Expert predictions with real-time stock, futures, and metals, energy data to help you quickly recover and grow. Motoric cognitive risk syndrome is newly identified, so experts still have a lot to learn before they can explain in detailwhat causes it and how it affects the body, Isaacson said. This is complicated by the lack of “definitive pathological biomarkers” for MCR thus far, Isaacson said.
But “several mechanisms might explain this association,” Leroy said. “Sleep plays a role in ‘cleaning up’ neurotoxins accumulated in the brain. In addition, previous studies have shown a greater accumulation of proteins associated with Alzheimer’s disease in sleep-deprived individuals.
“One possible alternative or additive way is through the activation of brain inflammatory response, which is observed in Alzheimer’s disease and related dementias,” Leroy said.
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It’s unclear why out of seven sleep components, daytime dysfunction was the only one significantly associated with MCR risk, when one might think that the other six components — which included sleep quality and quantity — would play a role in daytime dysfunction, experts said.
nihar info global limited (531083) vs yyy ✌️【Long-Term Investment】✌️ Expert predictions with real-time stock trend analysis to help you quickly select high-potential stocks and grow capital. Spires-Jones pointed out that for the potential link between daytime dysfunction and MCR,reverse causation is also possible.
“Scientific evidence is suggesting that when you are in the early stages of dementia, pathological changes in the brain disrupt sleep,” she added — meaning it’s “likely the early disease causing sleep disruption, not disruption causing disease.”
It’s well known that sleep disturbances such asREM sleep behavior disordercan be early predictors of conditions includingLewy body dementiaor Parkinson’s disease, Isaacson said.
People havingtrouble with their sleepshould talk to their doctors, consider completing a sleep questionnaire, and discuss whether an at-home or in-hospital sleep study may be helpful, Isaacson said.
“There are now many treatments, both drug and non-drug approaches, that may be able to help depending on the exact problem found,” he added. “Treating sleep disturbances should pay dividends for many years, even decades, on overall brain health and dementia prevention.”
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“Living a healthy lifestyle including eating well, maintaining a healthy weight, keeping your body and brain active, and treating any hearing loss are all ways of boosting brain resilience and likely lowering dementia risk,” Spires-Jones said.
“This is not to blame people who have dementia for their lifestyle choices,” she added. “Best estimates indicate that less than half of the risk of dementia is due to this type of modifiable risk factor with the rest of the risk likely due to genes we inherit.”
However, given thepotential to modify your riskand the growth of medical research and treatments, Spires-Jones added, there is reason to be hopeful.
If you’re already experiencing mobility issues, fall prevention can help, Isaacson said — that can include physical and occupational therapy evaluation, and at-home adaptations such as installing bars in the shower, removing clutter and using night-lights.
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