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In a previously unpublished two-page manuscript dating to 1667, Newton wrote that to cure the plague, “the best is a toad suspended by the legs in a chimney for three days, which at last vomited up earth with various insects in it, onto a dish of yellow wax, and shortly after died.”

“Combining powdered toad with the excretions and serum made into lozenges and worn about the affected area, drove away the contagion and drew out the poison,” Newton noted in the document.

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“I think certainly that the current medical situation has an impact on people’s interest in reading about the history of it,” Darren Sutherland, a senior specialist in books and manuscripts at Bonhams, told 【 - Free Stock Portfolio Optimization 】.

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“There had to be some kind of spark of interest in that moment, just for his intellect. While medicine was never a focus of his, I think there was a personal attraction to this particular subject at the time,” Sutherland said.

Using toad vomit or gemstones to cure the plague sure does sound kooky today, but Newton “wasn’t an outlier in the context of the 17th century,” Sutherland said.

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“We usually associate him with what we think of as very modern, forward-looking science, but when he was alive, the lines between what we would now consider science and superstition are much, much blurrier.”

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Paracelsus “believed that the plague was caused by celestial disturbances on the body and that wearing a specific amulet could help disrupt the detrimental connection between the body and the stars,” Brander told 【 - Free Stock Portfolio Optimization 】.

“We’ve since moved away from this idea of sympathetic forces creating certain disturbances in the physical body, but it made sense in the early modern period. Newton was in the middle of this transitional time period where the body of scientific knowledge was still in flux, which was very exciting,” she added.

Differentiating between Newton’s scientific accomplishments and his musings on toads and gemstones is only possible to us as contemporary observers, with the benefit of hindsight.

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