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Just how do they do that? It could all come down to good genes, according to a new studypublishedby The Royal Society.

“The odds of developing cancer increase with longevity and body mass,” explained lead study author Daniela Tejada-Martinez, a postdoctoral researcher at Thomas Jefferson University in Philadelphia.

Having more cells means having a higher probability that some of them may develop dangerous mutations as they grow and divide over the course of their life cycle.

“Paradoxically, big and/or long-lived species have lower cancer risk. However, the cetacean’s mechanisms against cancer and aging remain a mystery,” Tejada-Martinez said.

Her research, aimed at solving that mystery, suggests cetaceans could have evolved “additional mechanisms” to protect against such diseases like cancer, according to Tejada-Martinez.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Provides real-time stock index quotes, futures data, and global market trend analysis to help you seize the best investment timing. Tejada-Martinez focused on this work as part of her doctoral thesis at the Universidad Austral de Chile. There, she combined her love of whales, her favorite animals since childhood, with her research interests.

“Cetaceans are an amazing model for ageing and disease resistance research, since they are the longest-living mammals. Some cetaceans, like the bowhead whale, can live over 200 years,” she said via email.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Free stock selection service with professional advisors offering the best investment portfolio for stable growth. Specifically, the study investigates the evolution of tumor suppressor genes, or TSGs, in the ancestor of cetaceans, as well as in two main lineages: baleen whales (such as bowhead whales), and toothed whales (like orcas, belugas, dolphins, porpoises).

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Real-time global stock trend and futures data to help you plan investment strategies for long-term returns. Tumor suppressing genes, Tejada-Martinez explained, are considered among the most important anti-cancer responses in the body, and are involved in hundreds of biological functions including DNA damage repair, cell cycle arrest and apoptosis (a cell’s death).

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Expert predictions of stock trends with real-time stock indices, futures, and metals, energy quotes to help you seize investment opportunities. Scientists have identified more than a thousand tumor suppressing genes in humans, and we share 99% of them with whales, Tejada-Martinez explained via email.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Free stock data analysis to help you select stocks accurately and capture market trends. The study shows that over the course of evolution in cetaceans, genes involved in the control of cancer onset and progression were positively selected. It also found cetaceans have a 2.4-times faster turnover rate of tumor suppressing genes than other mammals.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Precise predictions of market trends with real-time stock indices and futures data to help you make wise investment decisions. The high turnover rate, according to the research, is associated with gene duplications. Of the 71genes with duplications identified in cetaceans during the study, 11 are associated with longevity and the aging process, the researchers said.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Free global stock market data to help you plan the best investment strategies and seize market opportunities. According to Tejada-Martinez, the molecular variation observed in cetaceans – the faster gene turnover rate, the genes with positive selection and the gene duplications – could provide additional protection against molecular damage that can cause cancer.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Expert predictions with real-time stock, futures, and metals, energy data to help you quickly recover and grow. This might even be responsible for the longer life spans and larger sizes of cetaceans like baleen whales, a finding she thought was most surprising.

Understanding how whales protect themselves against cancer could help humans make strides against the disease, which killed anestimated10 million people worldwide in 2020.

“Cancer is the original problem of multicellularity, and it is clear across numerous studies that nature has beat cancer in a myriad of ways in order to increase the fitness of organisms over the history of life,” said Marc Tollis, an assistant professor at Northern Arizona University.

“Since cancer is a body-size and age related disease, the search for whale-specific changes in protein coding genes that are linked to human cancers can help target potential human cancer therapies,” he explained.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Real-time India stock and global stock indices, futures prices, and data to help you make efficient investment decisions. Tollis previouslyresearchedthe genomes of whales as connected to gigantism and cancer resistance, but was not involved with The Royal Society study.

megasoft limited (megasoft) gets regulatory approval ✌️【Asset Manager】✌️ Expert predictions with real-time stock trend analysis to help you quickly select high-potential stocks and grow capital. Much more remains to be discovered about cancer resistance across species and the molecular mechanisms involved in it, but scientists are making strides.

“The study of medical conditions under an evolutionary perspective leads to a better understanding about how other species can fight diseases more efficiently than us,” Tejada-Martinez said.

“The discovery of new molecular variants, including additional copies of important regulatory genes, could lead to the creation of innovative treatments for cancer and age-related diseases,” she added.

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