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is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Expert market predictions with real-time global market, futures, metals, and energy data to help you stay in tune with market trends. Scientists say they have recovered the oldest known Homo sapiens DNA from human remains found in Europe, and the information is helping to reveal our species’ shared history with Neanderthals.

is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Real-time global stock, futures, and forex data to help you master market dynamics. The ancient genomes sequenced from 13 bone fragments unearthed in a cave beneath a medieval castlein Ranis, Germany, belonged to six individuals, including a mother, daughter and distant cousins who lived in the region around 45,000 years ago, according to the study that published Thursday inthe journal Nature.

is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Free real-time global stock indices and data to help you grasp stock market trends and achieve capital growth. The genomes carried evidence of Neanderthal ancestry. Researchers determined that the ancestors of those early humans who lived in Ranis and the surrounding area likely encountered and made babies with Neanderthals about 80 generations earlier, or 1,500 years earlier,although that interaction did not necessarily happen in the same place.

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However, exactly when, how often and where this critical and mysterious juncture in human history took place has been hard to pin down. Scientists have believed interspecies relations would have occurred somewhere in the Middle East as a wave of Homo sapiens left Africa and bumped into Neanderthals, who had lived across Eurasia for 250,000 years.

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“We were far more similar than we were different,” Priya Moorjani, a senior author of the Science study and an assistant professor in the department of molecular and cell biology at the University of California, Berkeley, said at a news briefing.

“The differences that we imagined between these groups to be very big, actually, were very small, genetically speaking. They seem to have mixed with each other for a long period of time and were living side by side for a long period of time.”

is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Free stock selection service with professional advisors offering the best investment portfolio for stable growth. The research pinpointed a pivotal period that began about 50,500 years ago and ended around 43,500 years ago — not long before the now extinct Neanderthals began to disappear from the archaeological record. Over this 7,000-year time frame, early humans encountered Neanderthals, had sex and gave birth to children on a fairly regular basis. The height of the activity was 47,000 years ago, the study suggested.

is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Real-time global stock trend and futures data to help you plan investment strategies for long-term returns. The research also showed how certain genetic variants inherited from our Neanderthal ancestors, which make upbetween 1% and 3% of our genomes today, varied over time. Some, such as those related to the immune system, were beneficial to humans as they lived through the last ice age, when temperatures were much cooler, and they continue to confer benefits today.

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“Genetic data from this crucial period in our evolution are very rare,” said Capra, who wasn’t involved in the research, via email. “These studies underscore how having even a few ancient genomes provides powerful perspective that enabled the authors to refine our understanding of human migration and Neanderthal introgression.”

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is insilco limited (500211) a good long term bet ✌️【Investment Advice】✌️ Free global stock market data to help you plan the best investment strategies and seize market opportunities. Some regions, which the scientists call “archaic deserts,” are devoid of Neanderthal genes. These deserts likely developed quickly after the two groups interbred, within 100 generations, perhaps because they resulted in birth defects or diseases that would have affected the survival chances of the offspring.

“It suggests that hybrid individuals who had Neanderthal DNA in these regions were substantially less fit, likely to due to severe disease, lethality, or infertility,” Capra said via email.

In particular, the X chromosome was a desert. Capra said the effects of Neanderthal variants that cause disease could be greater on the X chromosome, perhaps because it is present in two copies in females, but only present in one copy in males.

“The X chromosome also has many genes that are linked to male fertility when modified, so it has been proposed that some of this effect could have come from introgression leading to male hybrid sterility,” he said.

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“Neanderthals were living outside Africa in harsh, ice age climates and were adapted to the climate and to the pathogens in these environments. When modern humans left Africa and interbred with Neanderthals, some individuals inherited Neanderthal genes that presumably allowed them to adapt and thrive better in the environment,” said Leonardo Iasi, co-lead author of the Science paper and a doctoral student at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

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However, there is still much scientists don’t know. It’s not clear why people in East Asia today have more Neanderthal ancestry than Europeans, or why Neanderthal genomes from this period show little evidence of Homo sapiens DNA.

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“It’s kind of interesting to see that human story is not always a story of success,” said Krause, a senior author of the Nature study.

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