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Five years after launching the startup, the government approved an oral vaccine her team created that’s designed for the world’s beekeepers to feed to worker bees, which then feed it to their queens in royal jelly.
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Now, she’s on a mission to get as many bees vaccinated as she can — helping to safeguard not only the hives but the crops that they pollinate.“We know that the loss of insects is dramatic for this world,” Kleiser said.
“We cannot survive on this planet or anywhere else without insects.”The Dalan vaccine defends against a devastating bacterial disease aptly named American Foulbrood, and Kleiser sees it as a first step toward keeping the roughly 3 million honeybee colonies in the U.S.
healthy.
It’s not the only disease bees can suffer from; about 50% of colonies and millions of bees die each year from a variety of ailments, including a nasty parasite called the varroa mite, pesticide poisoning, inadequate nutrition and the stress of traveling around the country to pollinate crops.
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“How do you combat that?”Kleiser and her team at Athens, Georgia-based Dalan Animal Health believe specially designed bee vaccines are an important tool in keeping more bees alive, enabling commercial beekeepers (who may have some 5,000 to 30,000 colonies) to continue bringing them around the country so they can pollinate crops like almonds, blueberries, cucumbers and apples.“If you have an outbreak [of American Foulbrood], the spores have such resiliency that the recommended treatment is to kill all the bees and burn all the hives,” said Tom Chi, founder of At One Ventures, who invested in a $3.6 million seed round in summer 2022 as Dalan was taking its vaccine against American Foulbrood through clinical trials.
“It’s catastrophic if you get it.”Kleiser, who has a Ph.D.
in neurophysiology from the Ludwig Maximilian University of Munich, discovered the research that would lead her to bee vaccines when she was working to help universities transform academic work into businesses.
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Insects and other invertebrates don’t have antibodies like humans and other mammals do, so the traditional way of creating vaccines won’t work on them.
“When I heard about the research, I was like, ‘Why isn’t anybody doing this?’” Kleiser recalled.“If someone cuts their winter losses in half because of these vaccinated queens, it would spread like wildfire.”Kleiser spun Freitak’s research out of the university, then they created a vaccine that’s mixed into the so-called “queen candy” for the queens’ attendants, who then incorporate it into the royal jelly that is fed to the queen.
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“This is really new.
I think that’s why it’s caused a lot of interest and excitement,” said Blake Shook, a commercial beekeeper in Leonard, Texas, who is testing out the new vaccine.
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