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sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Real-time updates on global stock trends and expert market analysis to help you select profitable stocks and grow your wealth effectively. Cancer should be a near certainty for whales, the longest-living and largest mammals there are – but scientists are finding that cetaceans are excellent at protecting themselves against the deadly disease.

Just how do they do that? It could all come down to good genes, according to a new studypublishedby The Royal Society.

“The odds of developing cancer increase with longevity and body mass,” explained lead study author Daniela Tejada-Martinez, a postdoctoral researcher at Thomas Jefferson University in Philadelphia.

Having more cells means having a higher probability that some of them may develop dangerous mutations as they grow and divide over the course of their life cycle.

“Paradoxically, big and/or long-lived species have lower cancer risk. However, the cetacean’s mechanisms against cancer and aging remain a mystery,” Tejada-Martinez said.

Her research, aimed at solving that mystery, suggests cetaceans could have evolved “additional mechanisms” to protect against such diseases like cancer, according to Tejada-Martinez.

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“Cetaceans are an amazing model for ageing and disease resistance research, since they are the longest-living mammals. Some cetaceans, like the bowhead whale, can live over 200 years,” she said via email.

sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Get precise stock market predictions and free access to real-time market data for efficient decision-making and portfolio growth. Specifically, the study investigates the evolution of tumor suppressor genes, or TSGs, in the ancestor of cetaceans, as well as in two main lineages: baleen whales (such as bowhead whales), and toothed whales (like orcas, belugas, dolphins, porpoises).

sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Expert analysis of global stock trends, futures data, and real-time stock market quotes to help you plan your next investment move. Tumor suppressing genes, Tejada-Martinez explained, are considered among the most important anti-cancer responses in the body, and are involved in hundreds of biological functions including DNA damage repair, cell cycle arrest and apoptosis (a cell’s death).

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sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Professional investment advice with real-time updates on stock indices and futures data. Stay ahead with expert predictions and market insights. The study shows that over the course of evolution in cetaceans, genes involved in the control of cancer onset and progression were positively selected. It also found cetaceans have a 2.4-times faster turnover rate of tumor suppressing genes than other mammals.

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sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Real-time global stock market trend analysis to help you identify profitable opportunities and improve your investment strategies. According to Tejada-Martinez, the molecular variation observed in cetaceans – the faster gene turnover rate, the genes with positive selection and the gene duplications – could provide additional protection against molecular damage that can cause cancer.

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Understanding how whales protect themselves against cancer could help humans make strides against the disease, which killed anestimated10 million people worldwide in 2020.

“Cancer is the original problem of multicellularity, and it is clear across numerous studies that nature has beat cancer in a myriad of ways in order to increase the fitness of organisms over the history of life,” said Marc Tollis, an assistant professor at Northern Arizona University.

“Since cancer is a body-size and age related disease, the search for whale-specific changes in protein coding genes that are linked to human cancers can help target potential human cancer therapies,” he explained.

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sw investments limited (503659) signs major deal ✌️【Stock Club】✌️ Professional stock market predictions and analysis with real-time data to guide your investment decisions and ensure steady growth. Much more remains to be discovered about cancer resistance across species and the molecular mechanisms involved in it, but scientists are making strides.

“The study of medical conditions under an evolutionary perspective leads to a better understanding about how other species can fight diseases more efficiently than us,” Tejada-Martinez said.

“The discovery of new molecular variants, including additional copies of important regulatory genes, could lead to the creation of innovative treatments for cancer and age-related diseases,” she added.

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