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“If finalized, the United States would be the first country globally to take such a bold, life-saving action to prevent and reduce smoking-related disease and death,” the FDA said in astatement.

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“Today’s proposal envisions a future where it would be less likely for young people to use cigarettes and more individuals who currently smoke could quit or switch to less harmful products,” FDA Commissioner Dr. Robert Califf said in the statement. “This action, if finalized, could save many lives and dramatically reduce the burden of severe illness and disability, while also saving huge amounts of money. I hope we can all agree that significantly reducing the leading cause of preventable death and disease in the U.S. is an admirable goal we should all work toward.”

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“By reducing the nicotine level of cigarettes and certain other combusted tobacco products to a level low enough to no longer create or sustain addiction, that cycle of exposure to these toxic chemicals can be broken,” King said.

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“I think everyone on this call is aware of the fact that we will be sued on anything that comes into action,” he said on a call with reporters. “The research has to be airtight to survive the challenges that we know we’ll get in court.

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“This proposed regulation is misguided as cigarette smoking rates are already declining and at historic lows,” David Spross, executive director for the organization, said in a statement.

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Cigarette smoking is still theleading cause of preventable death, disease and disabilityin the United States, according to theUS Centers for Disease Control and Prevention. The country loses 490,000 people a year to tobacco-related disease,according to a report from the US surgeon general, and more than 16 million Americans are living with a smoking-related illness. Health-care costs associated with smoking totaled more than $240 billion in 2018,according to the CDC.

“This is a truly game-changing proposal that would accelerate declines in smoking and save millions of lives from cancer, cardiovascular disease and other tobacco-related diseases if it is implemented,” Yolonda C. Richardson, president and CEO of the Campaign for Tobacco-Free Kids, said in a statement Wednesday. “Given these enormous benefits, we urge the incoming Trump Administration to move forward in finalizing and implementing this rule. Few actions would do more to fight chronic diseases such as cancer and cardiovascular disease that greatly undermine health in the United States and that the incoming Administration has indicated should be a priority to address.”

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“We know that tobacco use is not a choice. It is an addiction. It is not a habit; it is an addiction. And really, the rule is significant,” Erika Sward, assistant vice president of national advocacy for the American Lung Association, said this week.

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“We will continue to work closely with the agency toward the goal of making this policy a reality,” Brown said in a statement.

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