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“She had multiorgan failure and was horribly ill,” said Dr. Megan Ranney, an emergency medicine physician and dean of the Yale School of Public Health, who was not involved with the girl’s care.

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“Were those extraordinary treatment modalities not available, she likely would not have lived,” Ranney said.

Health officials in British Columbiaclosed their investigationinto the case late last month after being unable to find the virus in any of the household pets, nearby animals, or soil or water samples. Close monitoring of people who were around the teen determined that no one else caught the virus from her. At the time, it wasn’t clear whether she had recovered.

narayana hrudayalaya ltd ✌️【Return】✌️ Free stock market analysis and data updates to help you select the best investment portfolio. Achieve steady growth and avoid losses with expert predictions and real-time market insights. The new report on the teen’s case “clearly shows that a child who was otherwise generally healthy became sick and then got very, very ill in a matter of days. This is a very worrisome outcome that we should be much more concerned about happening with other infections,” said Dr. Jennifer Nuzzo, who directs the Pandemic Center at Brown University. She was not involved in the case.

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In both severe infections – the teen’s and the case in Louisiana – the virus has shown changes that mean it might be adapting to humans, a finding that has put infectious disease experts on high alert since it increases the possibility of human-to-human spread.

“For this reason, we should be much more aggressive in conducting environmental surveillance for H5N1 to track the virus and to prevent people from becoming infected,” Nuzzo said.

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Eye redness, or conjunctivitis, was the most common symptom in these farmworker infections, showing up in 42 of 46 cases (93%). Almost half of the workers had fevers, and more than a third reported respiratory symptoms. The average duration of illness was about four days.

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In a commentary that accompanied the two studies, Dr. Jeanne Marrazzo, who directs the National Institute of Allergy and Infectious Diseases, says the mutations found in the virus isolated from the Canadian teen highlight an “urgent need for vigilant surveillance and assessment of the threat of human-to-human transmission.”

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“This kind of repetitive, persistent opportunity for passage from one species to another, from one anatomic space to another, that’s what that’s what influenza thrives on to mutate,” Marrazzo told 【 - Free Stock Movement Tracking 】. “This virus doesn’t miss a beat.”

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“The risk is really going to come when this gets better at obviously infecting humans, and then we are faced with potential for human-to-human transmission,” Marrazzo said.

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