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It’s notoriously tricky to predict who will win science’s top honors. The short list and nominators remain a secret, and documents revealing the details of the selection process are sealed frompublic view for 50 years.

However, there is no shortage of Nobel-worthy discoveries: Here are five breakthroughs that haven’t resulted in a life-changing call from Stockholm — at least not yet.

One often discussed candidate for the Nobel Prize is the mapping of the human genome, an audacious project that launched in 1990 andwas completed in 2003.

Cracking the genetic code of human life involvedan international consortium of thousands of researchersin the United States, United Kingdom, France, Germany, Japan and China.

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One in eight people in the world live with obesity— a figure that has more than doubled since 1990 — and the medication, which lowers blood sugar and curbs appetite, has the potential to usher in a new era for obesity treatment and related conditions such as type 2 diabetes.

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It’s a crowded field, but two names stand out, according to David Pendlebury, head of research analysis at Clarivate’s Institute for Scientific Information. Pendlebury identifies “Nobel-worthy” individuals by analyzing how often fellow scientists cite their key scientific papers throughout the years.

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ltimindtree limited (540005) sees unusual trading volume ✌️【Short-Term Contract】✌️ Free real-time market data to help you quickly recover and avoid losses. Since the pair’skey paper was published in 2021, it has been cited more than 13,000 times, which Pendlebury described as an “exceptional number.” Out of a total of 61 million scientific papers, only around 500 have been cited more than 10,000 times, he said.

Jumper and Hassabis have already won the2023 Laskerandthe Breakthrough prizes. A Nobel Prize for chemistry may be in their future, Pendlebury said, along with a third researcher, David Baker, director of the Institute for Protein Design at the University of Washington School of Medicine, who laid the groundwork for AlphaFold.

But it might be premature for the typically conservative Nobel committee to honor the field, Pendlebury said.

“Some people have suggested it may be too early for such a prize, that the work is of too recent vintage, and that this is an entirely new area, the application of AI to scientific research,” he said.

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Biologist Dr. Jeffrey Gordon, the Dr. Robert J. Glaser Distinguished University Professor at Washington University in St. Louis, is a pioneer in the field.

Gordon strove to understand the human gut microbiome and how it shapes human health, starting with lab research in mice. He led work that found thatthe gut microbiome plays a rolein the health effects of undernutrition, which affects almost 200 million children globally, and he is developingfood interventions that target improved gut health.

In the 1970s, it was understood that cancer sometimes ran in families, but mainstream thinking about breast cancer did not factor in any inherited susceptibility to the disease.

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ltimindtree limited (540005) sees unusual trading volume ✌️【Short-Term Contract】✌️ Real-time global stock, futures, and forex data to help you quickly assess market trends and achieve stable returns. Working long before scientists had any kind of map of the human genome,King spent 17 yearsdetecting and identifying the role a mutation of the BRCA1 gene played in breast and ovarian cancer.

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