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“It’s much ado about nothing and sensationalized in that way,” said Dr. Alex Keuroghlian, director of the Division of Education and Training at the Fenway Institute, a group that advocates for the heath needs of sexual and gender minorities and those affected by HIV.
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Olson-Kennedy said thatin the study, which she helped lead,puberty blockersdid not appear to improve the mental health of 95 children ages 8 to 16 who were followed for two years to understand their mental and physical functioning as doctors used the medications to delay the physical changes associated with puberty, including things like body hair growth, menstruation and a deepening voice.
“They’re in really good shape when they come in, and they’re in really good shape after two years,” Olson-Kennedy told the Times.
Her description appears to contradict the baseline characteristics of the 95 study participants, which werepublished in 2022. That paper reports that more than 1 in 4 had clinically significant levels of depression, anxiety and suicidal thoughts. About 8% had reported a previous suicide attempt.
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Dr. Amy Tishelman, a psychologist and research associate professor at Boston College, said that she understood the impulse to be cautious but that it’s critical to publish the data.
“I feel it’s imperative for research, especially research funded by taxpayer money, to be published for the integrity of science,” said Tishelman, who helped write the initial grant for the project, which is called “The Impact of Early Medical Treatment on Transgender Youth.” “We need to be forthright about our findings.”
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“Puberty blockers may have prevented a decline in mental health,” she said, especially for kids who may have had greater body dysphoria – or a sense of being in the wrong body – after puberty.
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For years, doctors have prescribed puberty-blocking drugs to certain transgender children who are psychologically assessed as needing them as a way to lower this distress, a model called the Dutch protocol, based on early research supporting this approach in the Netherlands.
In 2017, the Endocrine Society – a professional group of scientists and medical providers who focus on hormone-related issues – publisheda clinical practice guidelinethat cites more than 260 studies supporting the use of hormonal therapies to support children and teens with gender dysphoria as well as medications to blockpuberty.
“Puberty-delaying medication is a safe, generally reversible, and conservative approach that gives transgender and gender-diverse teenagers and their families more time to explore their options,” the Endocrine Society said in a statement Friday.
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Onerecent studyfound that these restrictions may have come at a cost, showing that suicide rates among youth have increased in states that have passed anti-transgender laws.
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“The real meaning of the story is that scientists may not be comfortable publishing data because of the political landscape right now in the country, and that’s very problematic,” she said.
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