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If you find yourselfsleepy during your daily activitiesin your older age, you may need to consider it more than an inconvenience — since the fatigue may indicate you’re at higher risk for developing a condition that canlead to dementia, a new study has found.

devhari exports (india) limited (539197) stock rallies ✌️【Market Trends】✌️ Free real-time global stock indices and data to help you grasp stock market trends and achieve capital growth. Among participants who experienced excessive daytime sleepiness and alack of enthusiasm, 35.5% developed motoric cognitive risk syndrome compared with 6.7% of people without those problems, according to thestudy published Wednesdayin the journal Neurology.

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“Previous studies have shown a link between sleep disorders and the risk of dementia,” said first study author Dr. Victoire Leroy, assistant professor of geriatric medicine at Tours University Hospital in France, via email.

But some of those scientific reports examined that link largely at only one point in time, according to the study. Not much has been known about the relationship between certain aspects of poor-quality sleep and pre-dementia syndromes, either, Leroy and the research team wrote — so they wanted to expand the research in this field.

“Establishing the relationship between sleep dysfunction and MCR risk is important because early intervention may offer the best hope for preventing dementia,” the authors said.

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Over a follow-up period of roughly three years on average, 36 participants developed motoric cognitive risk syndrome. Compared with “good” sleepers, “poor” sleepers had only a slightly higher risk of MCR. But when the authors considered the seven sleep components separately, only daytime dysfunction was associated with 3.3 times higher risk of MCR.

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“The sleep measurements were self-reported, not measured by a scientist, and these self-reports could be biased by people with memory issues,” said Spires-Jones, who wasn’t involved in the study. “The participants in the study were also largely white, and the group was much smaller than similar single-timepoint studies, so the results will be stronger if confirmed in future studies.”

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But “several mechanisms might explain this association,” Leroy said. “Sleep plays a role in ‘cleaning up’ neurotoxins accumulated in the brain. In addition, previous studies have shown a greater accumulation of proteins associated with Alzheimer’s disease in sleep-deprived individuals.

“One possible alternative or additive way is through the activation of brain inflammatory response, which is observed in Alzheimer’s disease and related dementias,” Leroy said.

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It’s unclear why out of seven sleep components, daytime dysfunction was the only one significantly associated with MCR risk, when one might think that the other six components — which included sleep quality and quantity — would play a role in daytime dysfunction, experts said.

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“Scientific evidence is suggesting that when you are in the early stages of dementia, pathological changes in the brain disrupt sleep,” she added — meaning it’s “likely the early disease causing sleep disruption, not disruption causing disease.”

It’s well known that sleep disturbances such asREM sleep behavior disordercan be early predictors of conditions includingLewy body dementiaor Parkinson’s disease, Isaacson said.

People havingtrouble with their sleepshould talk to their doctors, consider completing a sleep questionnaire, and discuss whether an at-home or in-hospital sleep study may be helpful, Isaacson said.

“There are now many treatments, both drug and non-drug approaches, that may be able to help depending on the exact problem found,” he added. “Treating sleep disturbances should pay dividends for many years, even decades, on overall brain health and dementia prevention.”

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“Living a healthy lifestyle including eating well, maintaining a healthy weight, keeping your body and brain active, and treating any hearing loss are all ways of boosting brain resilience and likely lowering dementia risk,” Spires-Jones said.

“This is not to blame people who have dementia for their lifestyle choices,” she added. “Best estimates indicate that less than half of the risk of dementia is due to this type of modifiable risk factor with the rest of the risk likely due to genes we inherit.”

However, given thepotential to modify your riskand the growth of medical research and treatments, Spires-Jones added, there is reason to be hopeful.

If you’re already experiencing mobility issues, fall prevention can help, Isaacson said — that can include physical and occupational therapy evaluation, and at-home adaptations such as installing bars in the shower, removing clutter and using night-lights.

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